Arquette was born in Chicago, Illinois, the girl of Lewis Arquette (1935-2001), an actor, and Brenda Olivia "Mardi" (née Nowak; 1939-1997), who was additionally concerned within the arts. Arquette's mother was jewish, from a family that immigrated from poland and Russia. Arquette's father was a convert to Islam from Catholicism; through him, Patricia is distantly associated with explorer Meriwether Lewis.Her paternal grandfather was comedian cliff Arquette; and her siblings are actors Rosanna, Alexis, Richmond, and David Arquette. As a child, her parents offered to get her braces for her teeth; however she refused, telling them she wished to own flaws because it would help her with character acting.
Arquette became pregnant at the age of twenty together with her son Enzo Rossi (born January 3, 1989), with then-boyfriend musician Paul Rossi.In April 1995, Arquette married Nicolas Cage (with whom she would later co-star in bringing Out the Dead in 1999). They separated after nine months, however acted as a couple in public until Cage filed for divorce in february 2000. The divorce petition was withdrawn, however Arquette filed once more in november 2000.
Arquette and actor Thomas Jane became engaged in 2002 and have a girl, Harlow Olivia Calliope (born february 23, 2003). Arquette and Jane afterward married on June twenty five, 2006, at the Palazzo Contarini in Venice, Italy. In January 2009, Arquette filed for divorce from Jane on the grounds of inconsistent differences, however the couple shortly reconciled and Arquette requested to abandon the divorce petition on july nine, 2009. However, on August thirteen, 2010, Jane's representative declared that Arquette and Jane had determined to proceed with a divorce due to “irreconcilable differences.” The divorce was finalized on july 1, 2011. The pair were granted joint custody of their kid.